David N. Levin received his Ph.D. in theoretical physics from Harvard University in 1970 and did research in quantum field theory until 1977, when he entered medical school at the University of Chicago. He joined the faculty after receiving an MD and completing radiology residency at the University. He is currently a Professor in the Department of Radiology and co-directs the University's Brain Research Imaging Center. This facility is equipped with a 3 T MRI scanner that is dedicated to brain research with functional MRI and MR spectroscopy.

Contact Information:
Department of Radiology
AMB Q301B (MC 2026)
5841 S. Maryland Avenue
Chicago, IL 60637
Fax: 773-702-1161
Email: d-levin@uchicago.edu
Other Links: http://www-radiology.uchicago.edu/faculty/Levin.html

Research Interests
Dr. Levin is interested in methodological aspects of brain imaging with MRI. His group is currently developing a new method of acquiring and analyzing functional MRI (fMRI) data. This technique makes it possible to detect brain activation in fMRI data in a nearly model-independent manner (i.e., without prior knowledge of mental event timing). He and his colleagues have also invented a new, more efficient method of acquiring and reconstructing MR images that exploits prior knowledge of the subject's anatomy. Various clinical applications of this technique are being investigated. His past research interests have included multimodality 3D brain imaging, computer-assisted neurosurgery, and image segmentation.

Recent Publications
Nagle, S.K. & Levin, D.N. A library of generalized Fourier sampling patterns for irregular 2D regions of support. Submitted for publication.

Uftring, S.J., Wachtel, S.R., Chu, D., McCandless, C., Levin, D.N., & de Wit, H. An fMRI study of the effect of amphetamine on brain activity. Submitted for publication.

Levin, D.N. & Uftring, S.J. (2001). Detecting brain activation in fMRI data without prior knowledge of mental event timing. NeuroImage, 13, 153-160.

Uftring, S.J., Chu, D., Alperin, N., & Levin, D.N. (2000). The mechanical state of intracranial tissues in elderly subjects studied by imaging CSF and brain pulsations. Magn. Reson. Imaging, 18, 991-996.

Chu, D., Huttenlocher, P.R., Levin, D.N., & Towle, V.L. (2000). Reorganization of hand somatosensory cortex following perinatal unilateral brain injury. Neuropediatrics, 31, 63-69.

Kuperman, V.Y., Nagle, S.K., Alley, M.T., Glover, G.H., & Levin, D.N. (1999). Locally-focused contrast-enhanced carotid MRA. J. Magn. Reson. Imaging, 9, 663-669.

Nagle, S.K. & Levin, D.N. (1999). Multiple region MRI. Magn. Reson. Med., 41, 774-786.

Chu, D., Levin, D.N., & Alperin, N. (1998). Assessment of the biomechanical state of intracranial tissues by dynamic MRI of cerebrospinal fluid pulsations: a phantom study. Magn. Reson. Imaging, 16, 1043-1048.

Kuperman, V.Y., Nagle, S.K., & Levin, D.N. (1998). Locally focused MRI of interventions. J. Magn. Reson. Imaging, 8, 1288-1295.

Selected Courses

Radiology - Lectures on MRI for Medical Students and Residents